The primary purpose of the review paper should not be to discuss treatment options. If it is then the APS you create could be deemed "editorial" in nature and subject to PAAB review. What is your intent? You should try to find a reference that discusses the disease only, not focussed on treatments. It may be exempt if all the treatments are balanced, see the Health Canada document The DIstinction Between Advertising and Other Activities 'Consumer Brochure'.
